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Baseline imbalance and heterogeneity are present in meta-analyses of randomized clinical trials examining the effects of exercise and medicines for blood pressure management
Randomized clinical trials attempt to reduce bias and create similar groups at baseline to infer causal effects. In meta-analyses, baseline imbalance may threaten the validity of the treatment effects. This meta-epidemiological study examined baseline imbalance in comparisons of exercise and antihyp...
Autores principales: | Wewege, Michael A., Hansford, Harrison J., Shah, Brishna, Gilanyi, Yannick L., Douglas, Susan R. G., Parmenter, Belinda J., McAuley, James H., Jones, Matthew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474297/ https://www.ncbi.nlm.nih.gov/pubmed/35882996 http://dx.doi.org/10.1038/s41440-022-00984-3 |
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