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Mathematical model for the relationship between single-cell and bulk gene expression to clarify the interpretation of bulk gene expression data
Background. Differential expression analysis is a standard approach in molecular biology. For example, genes whose expression levels differ between diseased and non-diseased samples are considered to be associated with that disease. On the other hand, differential variability analysis focuses on the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474327/ https://www.ncbi.nlm.nih.gov/pubmed/36147671 http://dx.doi.org/10.1016/j.csbj.2022.08.062 |