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Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study

BACKGROUND/AIMS: The adenoma detection rate (ADR) does not reflect the complete detection of every adenoma during colonoscopy; thus, many surrogate indicators have been suggested. This study investigated whether the ADR and surrogate quality indicators reflect the adenoma miss rate (AMR) when perfor...

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Autores principales: Han, Jae Hee, Kim, Hyun Gun, Ahn, Eu Mi, Park, Suyeon, Jeon, Seong Ran, Cha, Jae Myung, Kwak, Min Seob, Jung, Yunho, Shin, Jeong Eun, Shin, Hyun Deok, Cho, Young-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474487/
https://www.ncbi.nlm.nih.gov/pubmed/34933279
http://dx.doi.org/10.5009/gnl210287
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author Han, Jae Hee
Kim, Hyun Gun
Ahn, Eu Mi
Park, Suyeon
Jeon, Seong Ran
Cha, Jae Myung
Kwak, Min Seob
Jung, Yunho
Shin, Jeong Eun
Shin, Hyun Deok
Cho, Young-Seok
author_facet Han, Jae Hee
Kim, Hyun Gun
Ahn, Eu Mi
Park, Suyeon
Jeon, Seong Ran
Cha, Jae Myung
Kwak, Min Seob
Jung, Yunho
Shin, Jeong Eun
Shin, Hyun Deok
Cho, Young-Seok
author_sort Han, Jae Hee
collection PubMed
description BACKGROUND/AIMS: The adenoma detection rate (ADR) does not reflect the complete detection of every adenoma during colonoscopy; thus, many surrogate indicators have been suggested. This study investigated whether the ADR and surrogate quality indicators reflect the adenoma miss rate (AMR) when performing qualified colonoscopy. METHODS: We performed a prospective, multicenter, cross-sectional study of asymptomatic examinees aged 50 to 75 years who underwent back-to-back screening colonoscopies by eight endoscopists. The ADR and surrogate quality indicators, including polyp detection rate, total number of adenomas per colonoscopy, additional adenomas found after the first adenoma per colonoscopy (ADR-Plus), and total number of adenomas per positive participant, were calculated for the prediction of AMR. RESULTS: A total of 371 back-to-back colonoscopies were performed. There was a significant difference in ADRs (range, 44% to 75.4%; p=0.024), polyp detection rates (range, 56% to 86.9%; p=0.008) and adenomas per positive participants (range, 1.19 to 2.30; p=0.038), and a tendency of a difference in adenomas per colonoscopy (range, 0.62 to 1.31; p=0.051) and ADR-Plus (range, 0.13 to 0.70; p=0.054) among the endoscopists. The overall AMR was 20.1%, and AMRs were not different (range, 13.9 to 28.6; p>0.05) among the endoscopists. No quality indicators were significantly correlated with AMR. The number of adenomas found during the first colonoscopy was an independent factor for increased AMR (odds ratio, 1.79; p<0.001). CONCLUSIONS: The colonoscopy quality indicators were significantly different among high-ADR endoscopists, and none of the quality indicators reflected the AMR of good quality colonoscopy performances. The only factor influencing AMR was the number of adenomas detected during colonoscopy.
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spelling pubmed-94744872022-09-19 Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study Han, Jae Hee Kim, Hyun Gun Ahn, Eu Mi Park, Suyeon Jeon, Seong Ran Cha, Jae Myung Kwak, Min Seob Jung, Yunho Shin, Jeong Eun Shin, Hyun Deok Cho, Young-Seok Gut Liver Original Article BACKGROUND/AIMS: The adenoma detection rate (ADR) does not reflect the complete detection of every adenoma during colonoscopy; thus, many surrogate indicators have been suggested. This study investigated whether the ADR and surrogate quality indicators reflect the adenoma miss rate (AMR) when performing qualified colonoscopy. METHODS: We performed a prospective, multicenter, cross-sectional study of asymptomatic examinees aged 50 to 75 years who underwent back-to-back screening colonoscopies by eight endoscopists. The ADR and surrogate quality indicators, including polyp detection rate, total number of adenomas per colonoscopy, additional adenomas found after the first adenoma per colonoscopy (ADR-Plus), and total number of adenomas per positive participant, were calculated for the prediction of AMR. RESULTS: A total of 371 back-to-back colonoscopies were performed. There was a significant difference in ADRs (range, 44% to 75.4%; p=0.024), polyp detection rates (range, 56% to 86.9%; p=0.008) and adenomas per positive participants (range, 1.19 to 2.30; p=0.038), and a tendency of a difference in adenomas per colonoscopy (range, 0.62 to 1.31; p=0.051) and ADR-Plus (range, 0.13 to 0.70; p=0.054) among the endoscopists. The overall AMR was 20.1%, and AMRs were not different (range, 13.9 to 28.6; p>0.05) among the endoscopists. No quality indicators were significantly correlated with AMR. The number of adenomas found during the first colonoscopy was an independent factor for increased AMR (odds ratio, 1.79; p<0.001). CONCLUSIONS: The colonoscopy quality indicators were significantly different among high-ADR endoscopists, and none of the quality indicators reflected the AMR of good quality colonoscopy performances. The only factor influencing AMR was the number of adenomas detected during colonoscopy. Editorial Office of Gut and Liver 2022-09-15 2021-12-21 /pmc/articles/PMC9474487/ /pubmed/34933279 http://dx.doi.org/10.5009/gnl210287 Text en Copyright © Gut and Liver. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Han, Jae Hee
Kim, Hyun Gun
Ahn, Eu Mi
Park, Suyeon
Jeon, Seong Ran
Cha, Jae Myung
Kwak, Min Seob
Jung, Yunho
Shin, Jeong Eun
Shin, Hyun Deok
Cho, Young-Seok
Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study
title Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study
title_full Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study
title_fullStr Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study
title_full_unstemmed Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study
title_short Correlation between Surrogate Quality Indicators for Adenoma Detection Rate and Adenoma Miss Rate in Qualified Colonoscopy, CORE Study: KASID Multicenter Study
title_sort correlation between surrogate quality indicators for adenoma detection rate and adenoma miss rate in qualified colonoscopy, core study: kasid multicenter study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474487/
https://www.ncbi.nlm.nih.gov/pubmed/34933279
http://dx.doi.org/10.5009/gnl210287
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