Cargando…
Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila
N(6)-methyladenosine (m(6)A), the most prevalent internal modification on eukaryotic mRNA, plays an essential role in various stress responses. The brain is uniquely vulnerable to cellular stress, thus defining how m(6)A sculpts the brain’s susceptibility may provide insight to brain aging and disea...
Autores principales: | Perlegos, Alexandra E., Shields, Emily J., Shen, Hui, Liu, Kathy Fange, Bonini, Nancy M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474545/ https://www.ncbi.nlm.nih.gov/pubmed/36104353 http://dx.doi.org/10.1038/s41467-022-33085-3 |
Ejemplares similares
-
Alternative splicing of METTL3 explains apparently METTL3-independent m(6)A modifications in mRNA
por: Poh, Hui Xian, et al.
Publicado: (2022) -
METTL3-dependent m(6)A modification programs T follicular helper cell differentiation
por: Yao, Yingpeng, et al.
Publicado: (2021) -
METTL3-mediated m(6)A modification is required for cerebellar development
por: Wang, Chen-Xin, et al.
Publicado: (2018) -
Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence
por: McGurk, Leeanne, et al.
Publicado: (2021) -
METTL14-dependent m(6)A modification controls iNKT cell development and function
por: Cao, Liang, et al.
Publicado: (2022)