Empagliflozin induces apoptotic-signaling pathway in embryonic vasculature: In vivo and in silico approaches via chick’s yolk sac membrane model

The present investigation was conducted to evaluate the vascular-toxicity of empagliflozin (EMP) in embryonic vasculature. Firstly, the vascular-toxicity of the drug as well as its interaction with apoptotic regulator proteins was predicted via in silico approach. In the next step, the apoptotic-sig...

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Detalles Bibliográficos
Autores principales: Mosallanejad, Saeedeh, Mahmoodi, Mehdi, Tavakkoli, Hadi, Khosravi, Ahmad, Salarkia, Ehsan, Keyhani, Alireza, Dabiri, Shahriar, Gozashti, Mohammad Hossein, Pardakhty, Abbas, Khodabandehloo, Hadi, Pourghadamyari, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474685/
https://www.ncbi.nlm.nih.gov/pubmed/36120349
http://dx.doi.org/10.3389/fphar.2022.970402

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