Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens

Delamanid and bedaquiline are two drugs approved to treat drug‐resistant tuberculosis, and each have been associated with corrected QT interval (QTc) prolongation. We aimed to investigate the relationships between the drugs' plasma concentrations and the prolongation of observed QT interval cor...

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Detalles Bibliográficos
Autores principales: Tanneau, Lénaïg, Karlsson, Mats O., Rosenkranz, Susan L., Cramer, Yoninah S., Shenje, Justin, Upton, Caryn M., Morganroth, Joel, Diacon, Andreas H., Maartens, Gary, Dooley, Kelly E., Svensson, Elin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474693/
https://www.ncbi.nlm.nih.gov/pubmed/35687528
http://dx.doi.org/10.1002/cpt.2685

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