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Associations between locus coeruleus integrity and diagnosis, age, and cognitive performance in older adults with and without late-life depression: An exploratory study

Late-life depression (LLD) is a risk factor for age-dependent cognitive deterioration. Norepinephrine-related degeneration in the locus coeruleus (LC) may explain this link. To examine the LC norepinephrine system in vivo, we acquired neuromelanin-sensitive MRI (NM-MRI) in a sample of 48 participant...

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Detalles Bibliográficos
Autores principales: Calarco, Navona, Cassidy, Clifford M., Selby, Ben, Hawco, Colin, Voineskos, Aristotle N., Diniz, Breno S., Nikolova, Yuliya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474922/
https://www.ncbi.nlm.nih.gov/pubmed/36088841
http://dx.doi.org/10.1016/j.nicl.2022.103182