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Associations between locus coeruleus integrity and diagnosis, age, and cognitive performance in older adults with and without late-life depression: An exploratory study
Late-life depression (LLD) is a risk factor for age-dependent cognitive deterioration. Norepinephrine-related degeneration in the locus coeruleus (LC) may explain this link. To examine the LC norepinephrine system in vivo, we acquired neuromelanin-sensitive MRI (NM-MRI) in a sample of 48 participant...
Autores principales: | Calarco, Navona, Cassidy, Clifford M., Selby, Ben, Hawco, Colin, Voineskos, Aristotle N., Diniz, Breno S., Nikolova, Yuliya S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474922/ https://www.ncbi.nlm.nih.gov/pubmed/36088841 http://dx.doi.org/10.1016/j.nicl.2022.103182 |
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