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FBXW7 inactivation induces cellular senescence via accumulation of p53

F-box and WD repeat domain containing 7 (FBXW7) acts as a substrate receptor of SKP1-CUL1-F-box (SCF) E3 ubiquitin ligase and plays crucial roles in the regulation of several cellular processes, including cell growth, division, and differentiation, by targeting diverse key regulators for degradation...

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Detalles Bibliográficos
Autores principales:	Gong, Longyuan, Cui, Danrui, Liu, Dian, Shen, Xiao, Pan, Hui, Xiong, Xiufang, Zhao, Yongchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475035/ https://www.ncbi.nlm.nih.gov/pubmed/36104351 http://dx.doi.org/10.1038/s41419-022-05229-2

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