Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report

A patient presented with ulcerations of the buccal mucosae, palate and gingiva. A gingival biopsy confirmed the diagnosis as pemphigus vulgaris. Despite medication with systemic corticosteroids and mycophenolate mofetil, desquamative gingivitis persisted. Adjunct treatment with rituximab was therefo...

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Detalles Bibliográficos
Autores principales: Dolenc‐Voljč, Mateja, Povšič, Katja, Kučič, Alja Cmok, Gašperšič, Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475132/
https://www.ncbi.nlm.nih.gov/pubmed/36177086
http://dx.doi.org/10.1002/ccr3.6321
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author Dolenc‐Voljč, Mateja
Povšič, Katja
Kučič, Alja Cmok
Gašperšič, Rok
author_facet Dolenc‐Voljč, Mateja
Povšič, Katja
Kučič, Alja Cmok
Gašperšič, Rok
author_sort Dolenc‐Voljč, Mateja
collection PubMed
description A patient presented with ulcerations of the buccal mucosae, palate and gingiva. A gingival biopsy confirmed the diagnosis as pemphigus vulgaris. Despite medication with systemic corticosteroids and mycophenolate mofetil, desquamative gingivitis persisted. Adjunct treatment with rituximab was therefore introduced. Regular follow‐ups revealed no inflammatory gingival changes even 6 years later.
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spelling pubmed-94751322022-09-28 Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report Dolenc‐Voljč, Mateja Povšič, Katja Kučič, Alja Cmok Gašperšič, Rok Clin Case Rep Case Report A patient presented with ulcerations of the buccal mucosae, palate and gingiva. A gingival biopsy confirmed the diagnosis as pemphigus vulgaris. Despite medication with systemic corticosteroids and mycophenolate mofetil, desquamative gingivitis persisted. Adjunct treatment with rituximab was therefore introduced. Regular follow‐ups revealed no inflammatory gingival changes even 6 years later. John Wiley and Sons Inc. 2022-09-14 /pmc/articles/PMC9475132/ /pubmed/36177086 http://dx.doi.org/10.1002/ccr3.6321 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dolenc‐Voljč, Mateja
Povšič, Katja
Kučič, Alja Cmok
Gašperšič, Rok
Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
title Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
title_full Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
title_fullStr Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
title_full_unstemmed Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
title_short Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
title_sort pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475132/
https://www.ncbi.nlm.nih.gov/pubmed/36177086
http://dx.doi.org/10.1002/ccr3.6321
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