Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae

A chemical investigation on the kiwi endophytic fungus Bipolaris sp. Resulted in the isolation of eight new terpenoids (1–8) and five known analogues (9–13). Compounds 1–5 are novel sativene sesquiterpenoids containing three additional skeletal carbons, while compounds 4 and 5 are rare dimers. Compo...

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Autores principales: Yu, Jun-Jie, Wei, Wen-Ke, Zhang, Yu, Cox, Russell J., He, Juan, Liu, Ji-Kai, Feng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475172/
https://www.ncbi.nlm.nih.gov/pubmed/36118317
http://dx.doi.org/10.3389/fchem.2022.990734
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author Yu, Jun-Jie
Wei, Wen-Ke
Zhang, Yu
Cox, Russell J.
He, Juan
Liu, Ji-Kai
Feng, Tao
author_facet Yu, Jun-Jie
Wei, Wen-Ke
Zhang, Yu
Cox, Russell J.
He, Juan
Liu, Ji-Kai
Feng, Tao
author_sort Yu, Jun-Jie
collection PubMed
description A chemical investigation on the kiwi endophytic fungus Bipolaris sp. Resulted in the isolation of eight new terpenoids (1–8) and five known analogues (9–13). Compounds 1–5 are novel sativene sesquiterpenoids containing three additional skeletal carbons, while compounds 4 and 5 are rare dimers. Compounds 6–8 and 13 are sesterterpenoids that have been identified from this species for the first time. Compounds 4 and 5 showed antibacterial activity against kiwifruit canker pathogen Pseudomonas syringae pv. Actinidiae (Psa) with MIC values of 32 and 64 μg/ml, respectively.
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spelling pubmed-94751722022-09-16 Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae Yu, Jun-Jie Wei, Wen-Ke Zhang, Yu Cox, Russell J. He, Juan Liu, Ji-Kai Feng, Tao Front Chem Chemistry A chemical investigation on the kiwi endophytic fungus Bipolaris sp. Resulted in the isolation of eight new terpenoids (1–8) and five known analogues (9–13). Compounds 1–5 are novel sativene sesquiterpenoids containing three additional skeletal carbons, while compounds 4 and 5 are rare dimers. Compounds 6–8 and 13 are sesterterpenoids that have been identified from this species for the first time. Compounds 4 and 5 showed antibacterial activity against kiwifruit canker pathogen Pseudomonas syringae pv. Actinidiae (Psa) with MIC values of 32 and 64 μg/ml, respectively. Frontiers Media S.A. 2022-09-01 /pmc/articles/PMC9475172/ /pubmed/36118317 http://dx.doi.org/10.3389/fchem.2022.990734 Text en Copyright © 2022 Yu, Wei, Zhang, Cox, He, Liu and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Yu, Jun-Jie
Wei, Wen-Ke
Zhang, Yu
Cox, Russell J.
He, Juan
Liu, Ji-Kai
Feng, Tao
Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae
title Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae
title_full Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae
title_fullStr Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae
title_full_unstemmed Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae
title_short Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae
title_sort terpenoids from kiwi endophytic fungus bipolaris sp. and their antibacterial activity against pseudomonas syringae pv. actinidiae
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475172/
https://www.ncbi.nlm.nih.gov/pubmed/36118317
http://dx.doi.org/10.3389/fchem.2022.990734
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