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Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects

Fucosylation is a common glycan terminal modification, which has been reported to be inhibited by 2-fluorofucose (2FF) both in vivo and in vitro. The present study aimed to investigate the effect of 2FF on acetaminophen (APAP)-induced acute liver injury, and further clarified the possible mechanisms...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoguo, Tu, Mengjue, Shi, Jianan, Zhou, Hong, Meng, Guoliang, Gu, Jianguo, Wang, Yuqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475176/
https://www.ncbi.nlm.nih.gov/pubmed/36120347
http://dx.doi.org/10.3389/fphar.2022.939317