Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt‐mTOR signaling pathway

BACKGROUND: Fibulin‐4, namely, EFEMP2, is an essential matricellular protein associated with a variety of malignancies. The aim of this study was to explore the role of fibulin‐4 in the progression of esophageal squamous cell carcinoma (ESCC), as well as its effect on ESCC sensitivity to apatinib tr...

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Detalles Bibliográficos
Autores principales: Chen, Xiangyu, Wang, Jianyu, Song, Liang, Yu, Yang, Shi, Mo, Jiang, Wenpeng, Liu, Xiangyan, He, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475232/
https://www.ncbi.nlm.nih.gov/pubmed/35950373
http://dx.doi.org/10.1111/1759-7714.14595

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