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Highly Sensitive EGFRvIII Detection in Circulating Extracellular Vesicle RNA of Glioma Patients

PURPOSE: Liquid biopsy offers an attractive platform for noninvasive tumor diagnosis, prognostication, and prediction of glioblastoma clinical outcomes. Prior studies report that 30% to 50% of GBM lesions characterized by EGFR amplification also harbor the EGFRvIII mutation. EXPERIMENTAL DESIGN: A n...

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Detalles Bibliográficos
Autores principales: Batool, Syeda Maheen, Muralidharan, Koushik, Hsia, Tiffany, Falotico, Sarah, Gamblin, Austin S., Rosenfeld, Yulia B., Khanna, Sirena K., Balaj, Leonora, Carter, Bob S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475243/
https://www.ncbi.nlm.nih.gov/pubmed/35849415
http://dx.doi.org/10.1158/1078-0432.CCR-22-0444