Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective Study

PURPOSE: Determine whether specific CTNNB1 or APC mutations in patients with desmoid tumor were associated with differences in clinical responses to systemic treatments. EXPERIMENTAL DESIGN: We established a multi-institutional dataset of previously treated patients with desmoid tumor across four U....

Descripción completa

Detalles Bibliográficos
Autores principales: Nathenson, Michael J., Hu, Junxiao, Ratan, Ravin, Somaiah, Neeta, Hsu, Robert, DeMaria, Peter J., Catoe, Heath W., Pang, Angela, Subhawong, Ty K., Amini, Behrang, Sweet, Kevin, Feister, Katharina, Malik, Karan, Jagannathan, Jyothi, Braschi-Amirfarzan, Marta, Sheren, Jamie, Caldas, Yupanqui, Moreno Tellez, Cristiam, Rosenberg, Andrew E., Lazar, Alexander J., Maki, Robert G., Benedetto, Pasquale, Cohen, Jonathan, Trent, Jonathan C., Ravi, Vinod, Patel, Shreyaskumar, Wilky, Breelyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475245/
https://www.ncbi.nlm.nih.gov/pubmed/35180772
http://dx.doi.org/10.1158/1078-0432.CCR-21-4504

Ejemplares similares

Ejemplares similares