Cargando…

GOLM1 depletion modifies cellular sphingolipid metabolism and adversely affects cell growth

Golgi membrane protein 1 (GOLM1) is a Golgi-resident type 2 transmembrane protein known to be overexpressed in several cancers, including hepatocellular carcinoma (HCC), as well as in viral infections. However, the role of GOLM1 in lipid metabolism remains enigmatic. In this study, we employed siRNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagaraj, Meghana, Höring, Marcus, Ahonen, Maria A., Nguyen, Van Dien, Zhou, You, Vihinen, Helena, Jokitalo, Eija, Liebisch, Gerhard, Nidhina Haridas, P.A., Olkkonen, Vesa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475319/
https://www.ncbi.nlm.nih.gov/pubmed/35948172
http://dx.doi.org/10.1016/j.jlr.2022.100259

Ejemplares similares