Cryo-EM structure of human hexameric MCM2-7 complex

The central step in the initiation of eukaryotic DNA replication is the loading of the minichromosome maintenance 2–7 (MCM2-7) complex, the core of the replicative DNA helicase, onto chromatin at replication origin. Here, we reported the cryo-EM structure of endogenous human single hexameric MCM2-7...

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Detalles Bibliográficos
Autores principales: Xu, Naining, Lin, Qingpeng, Tian, Honglei, Liu, Changdong, Wang, Peiyi, Suen, Ching Monica, Yang, Hongyu, Xiang, Ye, Zhu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475327/
https://www.ncbi.nlm.nih.gov/pubmed/36117988
http://dx.doi.org/10.1016/j.isci.2022.104976

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