Cargando…

SIRT3 expression alleviates microglia activation‑induced dopaminergic neuron injury through the mitochondrial pathway

The mitochondrial protein sirtuin 3 (SIRT3) can counteract cell damage caused by oxidative stress and inflammation, and contribute to cell survival primarily by improving mitochondrial function. However, the effects of SIRT3 in dopaminergic neuronal cells (DACs) remain unclear. In our previous studi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, De-Qi, Zang, Qing-Min, Jiang, Li-Lin, Lu, Cheng-Shu, Zhao, Shi-Hua, Xu, Lan-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475350/ https://www.ncbi.nlm.nih.gov/pubmed/36168411 http://dx.doi.org/10.3892/etm.2022.11598

Ejemplares similares

SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway
por: Jiang, De-Qi, et al.
Publicado: (2017)

M1 Microglia Induced Neuronal Injury on Ischemic Stroke via Mitochondrial Crosstalk between Microglia and Neurons
por: Liu, Wei, et al.
Publicado: (2022)

The inflammatory injury in the striatal microglia-dopaminergic-neuron crosstalk involved in Tourette syndrome development
por: Wang, Xueming, et al.
Publicado: (2023)

Overexpression of SIRT3 Suppresses Oxidative Stress-induced Neurotoxicity and Mitochondrial Dysfunction in Dopaminergic Neuronal Cells
por: Lee, Shinrye, et al.
Publicado: (2021)

Icariin Reduces Dopaminergic Neuronal Loss and Microglia-Mediated Inflammation in Vivo and in Vitro
por: Wang, Guo-Qing, et al.
Publicado: (2018)

Mitochondrial-dependent mechanisms are involved in angiotensin II-induced apoptosis in dopaminergic neurons
por: Ou, Zhou, et al.
Publicado: (2016)

Microglia-derived TNF-α contributes to RVLM neuronal mitochondrial dysfunction via blocking the AMPK–Sirt3 pathway in stress-induced hypertension
por: Wang, Linping, et al.
Publicado: (2023)

SKP-SCs transplantation alleviates 6-OHDA-induced dopaminergic neuronal injury by modulating autophagy
por: Ma, Chengxiao, et al.
Publicado: (2021)

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP
por: Yang, Xiaoxia, et al.
Publicado: (2018)

Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage
por: Yuan, Bin, et al.
Publicado: (2022)

Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation
por: Dai, Dongfang, et al.
Publicado: (2019)

Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC
por: Du, Fang, et al.
Publicado: (2018)

SIRT1 activation by 2,3,5,6-tetramethylpyrazine alleviates neuroinflammation via inhibiting M1 microglia polarization
por: Chen, Yu, et al.
Publicado: (2023)

Quercetin Attenuates Cardiac Hypertrophy by Inhibiting Mitochondrial Dysfunction Through SIRT3/PARP-1 Pathway
por: Chen, Wen-Jing, et al.
Publicado: (2021)

Matrine alleviates cisplatin‐induced acute kidney injury by inhibiting mitochondrial dysfunction and inflammation via SIRT3/OPA1 pathway
por: Yuan, Lu, et al.
Publicado: (2022)

Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation
por: Rocha, Sandra M., et al.
Publicado: (2016)

The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson’s Disease
por: Minakaki, Georgia, et al.
Publicado: (2020)

Sirt3 Protects Cortical Neurons against Oxidative Stress via Regulating Mitochondrial Ca(2+) and Mitochondrial Biogenesis
por: Dai, Shu-Hui, et al.
Publicado: (2014)

Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs
por: Fang, Du, et al.
Publicado: (2016)

FGF21 alleviates acute liver injury by inducing the SIRT1‐autophagy signalling pathway
por: Yang, Xiaoning, et al.
Publicado: (2022)

Tyrosine Metabolism Pathway Is Downregulated in Dopaminergic Neurons with LRRK2 Overexpression in Drosophila
por: Cheng, Jack, et al.
Publicado: (2023)

Osteopetrotic (op/op) mice have reduced microglia, no Aβ deposition, and no changes in dopaminergic neurons
por: Kondo, Yoichi, et al.
Publicado: (2007)

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation
por: de Pablos, Rocío M, et al.
Publicado: (2014)

Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia
por: Fan, Zheng, et al.
Publicado: (2017)

Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway
por: Zhang, Zheng-tao, et al.
Publicado: (2022)

Knockout of Sirt2 alleviates traumatic brain injury in mice
por: Wang, Wei, et al.
Publicado: (2022)

WKYMVm/FPR2 Alleviates Spinal Cord Injury by Attenuating the Inflammatory Response of Microglia
por: Zhang, Wenwu, et al.
Publicado: (2022)

Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3
por: Zhang, Chunmei, et al.
Publicado: (2021)

Minocycline Alleviates Cluster Formation of Activated Microglia and Age-dependent Dopaminergic Cell Death in the Substantia Nigra of Zitter Mutant Rat
por: Taguchi, Daisuke, et al.
Publicado: (2020)

Necrostatin-1 protection of dopaminergic neurons
por: Wu, Jing-ru, et al.
Publicado: (2015)

Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation through NF-κB signaling
por: Liang, Shi-Qian, et al.
Publicado: (2023)

Cdk5 phosphorylation-induced SIRT2 nuclear translocation promotes the death of dopaminergic neurons in Parkinson’s disease
por: Yan, Jianguo, et al.
Publicado: (2022)

Preventive Intrathecal Injection of Bupivacaine Alleviated Microglia Activation and Neuropathic Pain in a Rat Model of Chronic Constriction Injury
por: Wu, Chih-Cheng, et al.
Publicado: (2022)

Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway
por: Ru, Qin, et al.
Publicado: (2021)

The Impact of Mitochondrial Dysfunction on Dopaminergic Neurons in the Olfactory Bulb and Odor Detection
por: Paß, Thomas, et al.
Publicado: (2020)

Candidate Chinese Herbal Medicine Alleviates Methamphetamine Addiction via Regulating Dopaminergic and Serotonergic Pathways
por: Ru, Qin, et al.
Publicado: (2022)

Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial ROS Production
por: Chen, Dong, et al.
Publicado: (2019)

Apigenin Prevents Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway
por: Zhao, Licong, et al.
Publicado: (2020)

Neuronal Sirt3 Protects against Excitotoxic Injury in Mouse Cortical Neuron Culture
por: Kim, Sun Hee, et al.
Publicado: (2011)

Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages
por: Ma, Chuanrui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0c0n0aaaaatb0lst0a1naim7ef