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Design, synthesis, and evaluation of a novel PET imaging agent targeting lipofuscin in senescent cells

Promoting a senescent phenotype to suppress tumour progression may present an alternative strategy for treating cancer and encourages the development of positron emission tomography (PET) imaging biomarkers for assessing response to treatment. The accumulation of lipofuscin deposits in senescent cel...

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Detalles Bibliográficos
Autores principales:	Brickute, Diana, Chen, Cen, Braga, Marta, Barnes, Chris, Wang, Ning, Allott, Louis, Aboagye, Eric O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475417/ https://www.ncbi.nlm.nih.gov/pubmed/36275107 http://dx.doi.org/10.1039/d2ra04535d

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