Cargando…
Integrin β3-PKM2 pathway-mediated aerobic glycolysis contributes to mechanical ventilation-induced pulmonary fibrosis
Background: Mechanical ventilation (MV) can induce pulmonary fibrosis. This study aims to investigate whether MV-induced pulmonary fibrosis is associated with aerobic glycolysis and seeks to uncover the underlying mechanisms mediated by integrin β3-pyruvate kinase M2 (PKM2) pathway. Methods: PKM2 kn...
Autores principales: | Mei, Shuya, Xu, Qiaoyi, Hu, Yue, Tang, Ri, Feng, Jinhua, Zhou, Yang, Xing, Shunpeng, Gao, Yuan, He, Zhengyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475464/ https://www.ncbi.nlm.nih.gov/pubmed/36168620 http://dx.doi.org/10.7150/thno.72328 |
Ejemplares similares
-
ASK1-ER stress pathway-mediated fibrotic-EV release contributes to the interaction of alveolar epithelial cells and lung fibroblasts to promote mechanical ventilation-induced pulmonary fibrosis
por: Tang, Ri, et al.
Publicado: (2022) -
Fibrotic extracellular vesicles contribute to mechanical ventilation-induced pulmonary fibrosis development by activating lung fibroblasts via JNK signalling pathway: an experimental study
por: Tang, Ri, et al.
Publicado: (2023) -
Non-coding RNA alterations in extracellular vesicles from bronchoalveolar lavage fluid contribute to mechanical ventilation-induced pulmonary fibrosis
por: Tang, Ri, et al.
Publicado: (2023) -
Thy-1 depletion and integrin β3 upregulation-mediated PI3K-Akt-mTOR pathway activation inhibits lung fibroblast autophagy in lipopolysaccharide-induced pulmonary fibrosis
por: Wan, Hanxi, et al.
Publicado: (2019) -
A deep learning model for predicting COVID-19 ARDS in critically ill patients
por: Zhou, Yang, et al.
Publicado: (2023)