Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)

Meeting Diaryliodonium salts Chemistry with DNA‐Encoded Library DNA‐encoded library (DEL) is a powerful technique for hit discovery in medicinal chemistry. In article number 2202790, Hongtao Xu, Peixiang Ma, Wei Hou, Guang Yang, and co‐workers develope the first on‐DNA meeting diaryliodonium salts (...

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Detalles Bibliográficos
Autores principales: Xu, Hongtao, Tan, Tingting, Zhang, Yiyuan, Wang, Yan, Pan, Kangyin, Yao, Ying, Zhang, Shuning, Gu, Yuang, Chen, Wanting, Li, Jie, Dong, Hewei, Meng, Yu, Ma, Peixiang, Hou, Wei, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475511/
http://dx.doi.org/10.1002/advs.202270165
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author Xu, Hongtao
Tan, Tingting
Zhang, Yiyuan
Wang, Yan
Pan, Kangyin
Yao, Ying
Zhang, Shuning
Gu, Yuang
Chen, Wanting
Li, Jie
Dong, Hewei
Meng, Yu
Ma, Peixiang
Hou, Wei
Yang, Guang
author_facet Xu, Hongtao
Tan, Tingting
Zhang, Yiyuan
Wang, Yan
Pan, Kangyin
Yao, Ying
Zhang, Shuning
Gu, Yuang
Chen, Wanting
Li, Jie
Dong, Hewei
Meng, Yu
Ma, Peixiang
Hou, Wei
Yang, Guang
author_sort Xu, Hongtao
collection PubMed
description Meeting Diaryliodonium salts Chemistry with DNA‐Encoded Library DNA‐encoded library (DEL) is a powerful technique for hit discovery in medicinal chemistry. In article number 2202790, Hongtao Xu, Peixiang Ma, Wei Hou, Guang Yang, and co‐workers develope the first on‐DNA meeting diaryliodonium salts (DAI) chemistry and realize the selective arylation of phenols and oximes with both high yield and DNA fidelity via substrate activation strategy. [Image: see text]
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spelling pubmed-94755112022-09-28 Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022) Xu, Hongtao Tan, Tingting Zhang, Yiyuan Wang, Yan Pan, Kangyin Yao, Ying Zhang, Shuning Gu, Yuang Chen, Wanting Li, Jie Dong, Hewei Meng, Yu Ma, Peixiang Hou, Wei Yang, Guang Adv Sci (Weinh) Frontispiece Meeting Diaryliodonium salts Chemistry with DNA‐Encoded Library DNA‐encoded library (DEL) is a powerful technique for hit discovery in medicinal chemistry. In article number 2202790, Hongtao Xu, Peixiang Ma, Wei Hou, Guang Yang, and co‐workers develope the first on‐DNA meeting diaryliodonium salts (DAI) chemistry and realize the selective arylation of phenols and oximes with both high yield and DNA fidelity via substrate activation strategy. [Image: see text] John Wiley and Sons Inc. 2022-09-15 /pmc/articles/PMC9475511/ http://dx.doi.org/10.1002/advs.202270165 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Frontispiece
Xu, Hongtao
Tan, Tingting
Zhang, Yiyuan
Wang, Yan
Pan, Kangyin
Yao, Ying
Zhang, Shuning
Gu, Yuang
Chen, Wanting
Li, Jie
Dong, Hewei
Meng, Yu
Ma, Peixiang
Hou, Wei
Yang, Guang
Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
title Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
title_full Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
title_fullStr Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
title_full_unstemmed Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
title_short Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
title_sort metal‐free and open‐air arylation reactions of diaryliodonium salts for dna‐encoded library synthesis (adv. sci. 26/2022)
topic Frontispiece
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475511/
http://dx.doi.org/10.1002/advs.202270165
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