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Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022)
Engineered T Cells In article number 2201883, Hong Nam Kim, Hee Ho Park, Wonhwa Lee, and co‐workers present chimeric T cells stably expressing therapeutic peptides for treatment of severe infectious diseases. Using lentiviral system, T cells are engineered to express multi‐level therapeutic peptides...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475514/ http://dx.doi.org/10.1002/advs.202270168 |
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author | Kim, Hyelim Son, Boram Seo, Eun U Kwon, Miji Ahn, June Hong Shin, Heungsoo Song, Gyu Yong Park, Eun Ji Na, Dong Hee Cho, Seung‐Woo Kim, Hong Nam Park, Hee Ho Lee, Wonhwa |
author_facet | Kim, Hyelim Son, Boram Seo, Eun U Kwon, Miji Ahn, June Hong Shin, Heungsoo Song, Gyu Yong Park, Eun Ji Na, Dong Hee Cho, Seung‐Woo Kim, Hong Nam Park, Hee Ho Lee, Wonhwa |
author_sort | Kim, Hyelim |
collection | PubMed |
description | Engineered T Cells In article number 2201883, Hong Nam Kim, Hee Ho Park, Wonhwa Lee, and co‐workers present chimeric T cells stably expressing therapeutic peptides for treatment of severe infectious diseases. Using lentiviral system, T cells are engineered to express multi‐level therapeutic peptides with matrix metallopeptidases‐ and tumor necrosis factor alpha converting enzyme‐responsive cleavage sites on the surface. [Image: see text] |
format | Online Article Text |
id | pubmed-9475514 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94755142022-09-28 Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) Kim, Hyelim Son, Boram Seo, Eun U Kwon, Miji Ahn, June Hong Shin, Heungsoo Song, Gyu Yong Park, Eun Ji Na, Dong Hee Cho, Seung‐Woo Kim, Hong Nam Park, Hee Ho Lee, Wonhwa Adv Sci (Weinh) Inside Back Cover Engineered T Cells In article number 2201883, Hong Nam Kim, Hee Ho Park, Wonhwa Lee, and co‐workers present chimeric T cells stably expressing therapeutic peptides for treatment of severe infectious diseases. Using lentiviral system, T cells are engineered to express multi‐level therapeutic peptides with matrix metallopeptidases‐ and tumor necrosis factor alpha converting enzyme‐responsive cleavage sites on the surface. [Image: see text] John Wiley and Sons Inc. 2022-09-15 /pmc/articles/PMC9475514/ http://dx.doi.org/10.1002/advs.202270168 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Back Cover Kim, Hyelim Son, Boram Seo, Eun U Kwon, Miji Ahn, June Hong Shin, Heungsoo Song, Gyu Yong Park, Eun Ji Na, Dong Hee Cho, Seung‐Woo Kim, Hong Nam Park, Hee Ho Lee, Wonhwa Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) |
title | Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) |
title_full | Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) |
title_fullStr | Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) |
title_full_unstemmed | Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) |
title_short | Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia (Adv. Sci. 26/2022) |
title_sort | cleavage‐responsive biofactory t cells suppress infectious diseases‐associated hypercytokinemia (adv. sci. 26/2022) |
topic | Inside Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475514/ http://dx.doi.org/10.1002/advs.202270168 |
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