The Interaction between DNMT1 and High‐Mannose CD133 Maintains the Slow‐Cycling State and Tumorigenic Potential of Glioma Stem Cell

The quiescent/slow‐cycling state preserves the self‐renewal capacity of cancer stem cells (CSCs) and leads to the therapy resistance of CSCs. The mechanisms maintaining CSCs quiescence remain largely unknown. Here, it is demonstrated that lower expression of MAN1A1 in glioma stem cell (GSC) resulted...

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Detalles Bibliográficos
Autores principales: Wei, Yuanyan, Chen, Qihang, Huang, Sijing, Liu, Yingchao, Li, Yinan, Xing, Yang, Shi, Danfang, Xu, Wenlong, Liu, Weitao, Ji, Zhi, Wu, Bingrui, Chen, Xiaoning, Jiang, Jianhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475542/
https://www.ncbi.nlm.nih.gov/pubmed/35798319
http://dx.doi.org/10.1002/advs.202202216

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