SHF Acts as a Novel Tumor Suppressor in Glioblastoma Multiforme by Disrupting STAT3 Dimerization

Sustained activation of signal transducer and activator of transcription 3 (STAT3) is a critical contributor in tumorigenesis and chemoresistance, thus making it an attractive cancer therapeutic target. Here, SH2 domain‐containing adapter protein F (SHF) is identified as a tumor suppressor in gliobl...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Huang, Zixuan, Ji, Li, Chen, Cheng, Wan, Quan, Xin, Yu, Pu, Zhening, Li, Koukou, Jiao, Jiantong, Yin, Ying, Hu, Yaling, Gong, Lingli, Zhang, Rui, Yang, Xusheng, Fang, Xiangming, Wang, Mei, Zhang, Bo, Shao, Junfei, Zou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475553/
https://www.ncbi.nlm.nih.gov/pubmed/35843865
http://dx.doi.org/10.1002/advs.202200169

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