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Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties

[Image: see text] Flexible microfluidic chips have good application prospects in situations with easy bending and complex curvature. An important factor affecting the flexible microfluidic chip is its structural complexity. For example, the hybrid chip includes flow channels, mixing chambers, and on...

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Autores principales: Wang, Junyao, Cui, Bowen, Liu, Huan, Chen, Xingyu, Li, Yunpeng, Wang, Rui, Lang, Tianhong, Yang, Hanbo, lixiang Li, Pan, Hongxu, Quan, Jingran, Chen, Yansong, Xu, Jianxin, Liu, Yahao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475615/
https://www.ncbi.nlm.nih.gov/pubmed/36120004
http://dx.doi.org/10.1021/acsomega.2c02075
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author Wang, Junyao
Cui, Bowen
Liu, Huan
Chen, Xingyu
Li, Yunpeng
Wang, Rui
Lang, Tianhong
Yang, Hanbo
lixiang Li,
Pan, Hongxu
Quan, Jingran
Chen, Yansong
Xu, Jianxin
Liu, Yahao
author_facet Wang, Junyao
Cui, Bowen
Liu, Huan
Chen, Xingyu
Li, Yunpeng
Wang, Rui
Lang, Tianhong
Yang, Hanbo
lixiang Li,
Pan, Hongxu
Quan, Jingran
Chen, Yansong
Xu, Jianxin
Liu, Yahao
author_sort Wang, Junyao
collection PubMed
description [Image: see text] Flexible microfluidic chips have good application prospects in situations with easy bending and complex curvature. An important factor affecting the flexible microfluidic chip is its structural complexity. For example, the hybrid chip includes flow channels, mixing chambers, and one-way valves. How to achieve the same function with as few structures as possible has become an important research topic at present. In this paper, a Tesla valve micromixer with unidirectional flow characteristics is presented. A passive laminar flow Tesla valve micromixer is fabricated through 3D printing technology and limonene dissolution method. The main process is as follows: First of all, high impact polystyrene (HIPS) material was employed to make the Tesla valve channel mold. Second, the channel mold was dissolved in the limonene solvent. The mold of Tesla micromixer is made of HIPS material, the mixing experiment displace that the Tesla valve micromixer is characterized by unidirectional flow compared with the common T-shaped planar channel. At the same time, the 5-AAC Tesla valve micromixer can increase the mixing efficiency to 87%. By using four different groove structures and different flow rates of the mixing effect experiment, the conclusion is that the mixing efficiency of the 6-AAC Tesla valve micromixer is up to 0.89 when the flow rate is 2 mL/min. The results manifest that the Tesla valve structure can effectively improve the mixing efficiency.
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spelling pubmed-94756152022-09-16 Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties Wang, Junyao Cui, Bowen Liu, Huan Chen, Xingyu Li, Yunpeng Wang, Rui Lang, Tianhong Yang, Hanbo lixiang Li, Pan, Hongxu Quan, Jingran Chen, Yansong Xu, Jianxin Liu, Yahao ACS Omega [Image: see text] Flexible microfluidic chips have good application prospects in situations with easy bending and complex curvature. An important factor affecting the flexible microfluidic chip is its structural complexity. For example, the hybrid chip includes flow channels, mixing chambers, and one-way valves. How to achieve the same function with as few structures as possible has become an important research topic at present. In this paper, a Tesla valve micromixer with unidirectional flow characteristics is presented. A passive laminar flow Tesla valve micromixer is fabricated through 3D printing technology and limonene dissolution method. The main process is as follows: First of all, high impact polystyrene (HIPS) material was employed to make the Tesla valve channel mold. Second, the channel mold was dissolved in the limonene solvent. The mold of Tesla micromixer is made of HIPS material, the mixing experiment displace that the Tesla valve micromixer is characterized by unidirectional flow compared with the common T-shaped planar channel. At the same time, the 5-AAC Tesla valve micromixer can increase the mixing efficiency to 87%. By using four different groove structures and different flow rates of the mixing effect experiment, the conclusion is that the mixing efficiency of the 6-AAC Tesla valve micromixer is up to 0.89 when the flow rate is 2 mL/min. The results manifest that the Tesla valve structure can effectively improve the mixing efficiency. American Chemical Society 2022-08-28 /pmc/articles/PMC9475615/ /pubmed/36120004 http://dx.doi.org/10.1021/acsomega.2c02075 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Wang, Junyao
Cui, Bowen
Liu, Huan
Chen, Xingyu
Li, Yunpeng
Wang, Rui
Lang, Tianhong
Yang, Hanbo
lixiang Li,
Pan, Hongxu
Quan, Jingran
Chen, Yansong
Xu, Jianxin
Liu, Yahao
Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties
title Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties
title_full Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties
title_fullStr Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties
title_full_unstemmed Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties
title_short Tesla Valve-Based Flexible Microhybrid Chip with Unidirectional Flow Properties
title_sort tesla valve-based flexible microhybrid chip with unidirectional flow properties
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475615/
https://www.ncbi.nlm.nih.gov/pubmed/36120004
http://dx.doi.org/10.1021/acsomega.2c02075
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