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Vascular depression – regarding a case report
INTRODUCTION: Age-related vascular changes have long been documented as an etiopathogenic factor of some geriatric depressive syndromes. More recently, it has emerged the concept of “Vascular Depression” recognizing that cardiovascular disease may predispose, precipitate or perpetuate late life depr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475700/ http://dx.doi.org/10.1192/j.eurpsy.2021.1146 |
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author | Felgueiras, P. Martins, A. Miguel, A. Almeida, N. |
author_facet | Felgueiras, P. Martins, A. Miguel, A. Almeida, N. |
author_sort | Felgueiras, P. |
collection | PubMed |
description | INTRODUCTION: Age-related vascular changes have long been documented as an etiopathogenic factor of some geriatric depressive syndromes. More recently, it has emerged the concept of “Vascular Depression” recognizing that cardiovascular disease may predispose, precipitate or perpetuate late life depression. This condition was defined by an episode of major depressive disorder within the preceding 12 months in elderly with cardiovascular/cerebrovascular disease, or major cardiovascular risk factors. Vascular Depression isn`t described in DSM-V, and that difficults clinical recognition and affects clinically informed systematic studies. OBJECTIVES: Regarding a clinical case, we enphasize the clinical impact of Vascular Depression`s hypothesis. METHODS: We present a qualitative review of this topic using the Pubmed Central database. RESULTS: 74 years old male patient, with major depressive disorder about ten years. Depressive and cognitive symptoms didn`t respond to antidepressive treatment and his functional state has gradually declined. CONCLUSIONS: Vascular depression develops after the 60 – 65 years in the absence of personal and family history of affective disorder. The key symptoms are low energy, anhedonia, deficits in selfinitiation, psychomotor retardation, reduced processing speed and lack of insight into mood symptoms. Clinical assessment includes a review of history of vascular risk factors or/and disease, but also an imagiological evidence demonstrating subcortical white matter abnormalities. Insidious and chronic course tends to delay its recognition and management. This becomes critical because Vascular Depression is associated with poor response to antidepressant treatment and persistent depressive symptoms. It`s also associated with poor selfmanagement of comorbidities and impairment in daily function. Increased mortality from all causes is widely documented. |
format | Online Article Text |
id | pubmed-9475700 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94757002022-09-29 Vascular depression – regarding a case report Felgueiras, P. Martins, A. Miguel, A. Almeida, N. Eur Psychiatry Abstract INTRODUCTION: Age-related vascular changes have long been documented as an etiopathogenic factor of some geriatric depressive syndromes. More recently, it has emerged the concept of “Vascular Depression” recognizing that cardiovascular disease may predispose, precipitate or perpetuate late life depression. This condition was defined by an episode of major depressive disorder within the preceding 12 months in elderly with cardiovascular/cerebrovascular disease, or major cardiovascular risk factors. Vascular Depression isn`t described in DSM-V, and that difficults clinical recognition and affects clinically informed systematic studies. OBJECTIVES: Regarding a clinical case, we enphasize the clinical impact of Vascular Depression`s hypothesis. METHODS: We present a qualitative review of this topic using the Pubmed Central database. RESULTS: 74 years old male patient, with major depressive disorder about ten years. Depressive and cognitive symptoms didn`t respond to antidepressive treatment and his functional state has gradually declined. CONCLUSIONS: Vascular depression develops after the 60 – 65 years in the absence of personal and family history of affective disorder. The key symptoms are low energy, anhedonia, deficits in selfinitiation, psychomotor retardation, reduced processing speed and lack of insight into mood symptoms. Clinical assessment includes a review of history of vascular risk factors or/and disease, but also an imagiological evidence demonstrating subcortical white matter abnormalities. Insidious and chronic course tends to delay its recognition and management. This becomes critical because Vascular Depression is associated with poor response to antidepressant treatment and persistent depressive symptoms. It`s also associated with poor selfmanagement of comorbidities and impairment in daily function. Increased mortality from all causes is widely documented. Cambridge University Press 2021-08-13 /pmc/articles/PMC9475700/ http://dx.doi.org/10.1192/j.eurpsy.2021.1146 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Felgueiras, P. Martins, A. Miguel, A. Almeida, N. Vascular depression – regarding a case report |
title | Vascular depression – regarding a case report |
title_full | Vascular depression – regarding a case report |
title_fullStr | Vascular depression – regarding a case report |
title_full_unstemmed | Vascular depression – regarding a case report |
title_short | Vascular depression – regarding a case report |
title_sort | vascular depression – regarding a case report |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475700/ http://dx.doi.org/10.1192/j.eurpsy.2021.1146 |
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