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Is ketamine and lamotrigine interactions responsible for the sub-therapeutic effect of ketamine?

INTRODUCTION: The immediate antidepressant effect of Ketamine has become a breakthrough in the treatment of depression. Cytochrome CYP3A4 and 2B6 primarily metabolize Ketamine. OBJECTIVES: The present study explores potential pharmacokinetic and pharmacodynamic interactions of Lamotrigine and Ketami...

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Detalles Bibliográficos
Autores principales: Adnan, M., Motiwala, F., Mansuri, Z., Trivedi, C., Reddy, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475737/
http://dx.doi.org/10.1192/j.eurpsy.2021.1060