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Impact of cannabis consumption on the course of bipolar disorder
INTRODUCTION: Although one third of patients with Bipolar Disorder have an addiction to Cannabis or an abused consumption, the interaction between cannabis use and bipolar disorder remains controversial. OBJECTIVES: To evaluate the use of cannabis among patients with Bipolar Disorder and to compare...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475825/ http://dx.doi.org/10.1192/j.eurpsy.2021.1507 |
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author | Brahim, S. Aoun, M.H. Boukhchina, R. Frej, S. Ben Henia, M. Zarrouk, L. |
author_facet | Brahim, S. Aoun, M.H. Boukhchina, R. Frej, S. Ben Henia, M. Zarrouk, L. |
author_sort | Brahim, S. |
collection | PubMed |
description | INTRODUCTION: Although one third of patients with Bipolar Disorder have an addiction to Cannabis or an abused consumption, the interaction between cannabis use and bipolar disorder remains controversial. OBJECTIVES: To evaluate the use of cannabis among patients with Bipolar Disorder and to compare the socio-demographic and clinical characteristics between patients who are consumers and non-consumers. METHODS: This is a retrospective, descriptive study including all patients treated for type I bipolar disorder in the psychiatric department of Tahar Sfar Hospital of Mahdia (Tunisia). In addition to socio-demographic and clinical characteristics, we collected data on cannabis use (age at first consumption and frequency of consumption). RESULTS: Our study population consisted of 84 male patients followed for bipolar I disorder. The mean age was 36.8 ± 11.3 years. Among these patients, 23 (27.8%) had regular cannabis use. The average age at first consumption was 21.6 ± 7.2 years. Bipolar patients with regular cannabis consumption had an earlier age of onset of the disorder (p = 0.02). They had higher numbers of manic episodes (p = 0.05), higher number of manic episodes with severe intensity (p = 0.04), higher number of manic episodes with mixed characteristics(p = 0.04), a higher number of hospitalizations (p = 0.01) with longer hospital stays (p = 0.02). CONCLUSIONS: Cannabis use among patients with type 1 bipolar disorder is associated with an unfavorable course of the disorder. Early diagnosis and appropriate management of this comorbidity seem to be essential for improving the prognosis of bipolar disorder. |
format | Online Article Text |
id | pubmed-9475825 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94758252022-09-29 Impact of cannabis consumption on the course of bipolar disorder Brahim, S. Aoun, M.H. Boukhchina, R. Frej, S. Ben Henia, M. Zarrouk, L. Eur Psychiatry Abstract INTRODUCTION: Although one third of patients with Bipolar Disorder have an addiction to Cannabis or an abused consumption, the interaction between cannabis use and bipolar disorder remains controversial. OBJECTIVES: To evaluate the use of cannabis among patients with Bipolar Disorder and to compare the socio-demographic and clinical characteristics between patients who are consumers and non-consumers. METHODS: This is a retrospective, descriptive study including all patients treated for type I bipolar disorder in the psychiatric department of Tahar Sfar Hospital of Mahdia (Tunisia). In addition to socio-demographic and clinical characteristics, we collected data on cannabis use (age at first consumption and frequency of consumption). RESULTS: Our study population consisted of 84 male patients followed for bipolar I disorder. The mean age was 36.8 ± 11.3 years. Among these patients, 23 (27.8%) had regular cannabis use. The average age at first consumption was 21.6 ± 7.2 years. Bipolar patients with regular cannabis consumption had an earlier age of onset of the disorder (p = 0.02). They had higher numbers of manic episodes (p = 0.05), higher number of manic episodes with severe intensity (p = 0.04), higher number of manic episodes with mixed characteristics(p = 0.04), a higher number of hospitalizations (p = 0.01) with longer hospital stays (p = 0.02). CONCLUSIONS: Cannabis use among patients with type 1 bipolar disorder is associated with an unfavorable course of the disorder. Early diagnosis and appropriate management of this comorbidity seem to be essential for improving the prognosis of bipolar disorder. Cambridge University Press 2021-08-13 /pmc/articles/PMC9475825/ http://dx.doi.org/10.1192/j.eurpsy.2021.1507 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Brahim, S. Aoun, M.H. Boukhchina, R. Frej, S. Ben Henia, M. Zarrouk, L. Impact of cannabis consumption on the course of bipolar disorder |
title | Impact of cannabis consumption on the course of bipolar disorder |
title_full | Impact of cannabis consumption on the course of bipolar disorder |
title_fullStr | Impact of cannabis consumption on the course of bipolar disorder |
title_full_unstemmed | Impact of cannabis consumption on the course of bipolar disorder |
title_short | Impact of cannabis consumption on the course of bipolar disorder |
title_sort | impact of cannabis consumption on the course of bipolar disorder |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475825/ http://dx.doi.org/10.1192/j.eurpsy.2021.1507 |
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