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Cognitive decline and psychotropic drugs use in elderly people with mental disorders

INTRODUCTION: The growth in the number of aged people in the population is considered a worldwide phenomenon, with direct consequences in health systems. The literature indicates an increase in the diagnosis of mental disorders and the use of psychotropic drugs for that population, as well as freque...

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Autores principales: De Oliveira, K. Cestari, De Oliveira Bastos, P. Haidamus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476032/
http://dx.doi.org/10.1192/j.eurpsy.2021.1121
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author De Oliveira, K. Cestari
De Oliveira Bastos, P. Haidamus
author_facet De Oliveira, K. Cestari
De Oliveira Bastos, P. Haidamus
author_sort De Oliveira, K. Cestari
collection PubMed
description INTRODUCTION: The growth in the number of aged people in the population is considered a worldwide phenomenon, with direct consequences in health systems. The literature indicates an increase in the diagnosis of mental disorders and the use of psychotropic drugs for that population, as well as frequent complaints regarding to cognition. OBJECTIVES: To analyze the possible relationship between cognitive decline and use of psychiatric drugs in elderly with mental disorders, assisted by psychiatric outpatient clinics, city of Campo Grande, state of Mato Grosso do Sul, Brazil. METHODS: Quantitative, exploratory, descriptive and cross-sectional research, with 59 participants.Sociodemographic and clinical variables were collected through semi-structured clinical interviews and medical records. To screen for cognitive decline, the Mini Mental State Examination was used. RESULTS: Majority of females, with a mean age of 66.75 ± 0.63 years, married, up to 8 years of completed studies and living with family members. The prevalence of depressive disorders was higher (52.54%), with selective serotonin reuptake inhibitor antidepressant use in 67.8%. Most were using 2 or more psychotropics the most prevalent combination being benzodiazepines and antidepressants. 52.5% of the elderly reported cognitive complaints and 45.8% presented Mini Mental scores, suggesting cognitive decline. It was associated with depressive disorders and the consumption of 2 or more psychotropics. CONCLUSIONS: Although there is evidence that psychotropic drugs represent effective strategies for the treatment of mental disorders, the use for this group of elderly should be carefully analyzed, due to the predisposition or worsening of cognitive decline, with impairment to the quality of life of this population.
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spelling pubmed-94760322022-09-29 Cognitive decline and psychotropic drugs use in elderly people with mental disorders De Oliveira, K. Cestari De Oliveira Bastos, P. Haidamus Eur Psychiatry Abstract INTRODUCTION: The growth in the number of aged people in the population is considered a worldwide phenomenon, with direct consequences in health systems. The literature indicates an increase in the diagnosis of mental disorders and the use of psychotropic drugs for that population, as well as frequent complaints regarding to cognition. OBJECTIVES: To analyze the possible relationship between cognitive decline and use of psychiatric drugs in elderly with mental disorders, assisted by psychiatric outpatient clinics, city of Campo Grande, state of Mato Grosso do Sul, Brazil. METHODS: Quantitative, exploratory, descriptive and cross-sectional research, with 59 participants.Sociodemographic and clinical variables were collected through semi-structured clinical interviews and medical records. To screen for cognitive decline, the Mini Mental State Examination was used. RESULTS: Majority of females, with a mean age of 66.75 ± 0.63 years, married, up to 8 years of completed studies and living with family members. The prevalence of depressive disorders was higher (52.54%), with selective serotonin reuptake inhibitor antidepressant use in 67.8%. Most were using 2 or more psychotropics the most prevalent combination being benzodiazepines and antidepressants. 52.5% of the elderly reported cognitive complaints and 45.8% presented Mini Mental scores, suggesting cognitive decline. It was associated with depressive disorders and the consumption of 2 or more psychotropics. CONCLUSIONS: Although there is evidence that psychotropic drugs represent effective strategies for the treatment of mental disorders, the use for this group of elderly should be carefully analyzed, due to the predisposition or worsening of cognitive decline, with impairment to the quality of life of this population. Cambridge University Press 2021-08-13 /pmc/articles/PMC9476032/ http://dx.doi.org/10.1192/j.eurpsy.2021.1121 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
De Oliveira, K. Cestari
De Oliveira Bastos, P. Haidamus
Cognitive decline and psychotropic drugs use in elderly people with mental disorders
title Cognitive decline and psychotropic drugs use in elderly people with mental disorders
title_full Cognitive decline and psychotropic drugs use in elderly people with mental disorders
title_fullStr Cognitive decline and psychotropic drugs use in elderly people with mental disorders
title_full_unstemmed Cognitive decline and psychotropic drugs use in elderly people with mental disorders
title_short Cognitive decline and psychotropic drugs use in elderly people with mental disorders
title_sort cognitive decline and psychotropic drugs use in elderly people with mental disorders
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476032/
http://dx.doi.org/10.1192/j.eurpsy.2021.1121
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