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Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice
BACKGROUND: The massive loss of follicles in the early stage of ovarian tissue transplantation is considered a significant restriction to the efficacy of ovarian tissue cryopreservation (OTC) and transplantation (OT). The use of mesenchymal stem cells (MSCs) before transplantation of ovarian fragmen...
Autores principales: | Cheng, Jiaojiao, Ruan, Xiangyan, Li, Yanglu, Du, Juan, Jin, Fengyu, Gu, Muqing, Zhou, Qi, Xu, Xin, Yang, Yu, Wang, Husheng, Mueck, Alfred Otto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476266/ https://www.ncbi.nlm.nih.gov/pubmed/36104746 http://dx.doi.org/10.1186/s13287-022-03167-6 |
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