A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapy

BACKGROUND: Renal cell carcinoma (RCC) is a heterogeneous disease comprising histologically defined subtypes. For therapy selection, precise subtype identification and individualized prognosis are mandatory, but currently limited. Our aim was to refine subtyping and outcome prediction across main su...

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Detalles Bibliográficos
Autores principales: Büttner, Florian A., Winter, Stefan, Stühler, Viktoria, Rausch, Steffen, Hennenlotter, Jörg, Füssel, Susanne, Zastrow, Stefan, Meinhardt, Matthias, Toma, Marieta, Jerónimo, Carmen, Henrique, Rui, Miranda-Gonçalves, Vera, Kröger, Nils, Ribback, Silvia, Hartmann, Arndt, Agaimy, Abbas, Stöhr, Christine, Polifka, Iris, Fend, Falko, Scharpf, Marcus, Comperat, Eva, Wasinger, Gabriel, Moch, Holger, Stenzl, Arnulf, Gerlinger, Marco, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476269/
https://www.ncbi.nlm.nih.gov/pubmed/36109798
http://dx.doi.org/10.1186/s13073-022-01105-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476269/
https://www.ncbi.nlm.nih.gov/pubmed/36109798
http://dx.doi.org/10.1186/s13073-022-01105-y

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