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A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapy
BACKGROUND: Renal cell carcinoma (RCC) is a heterogeneous disease comprising histologically defined subtypes. For therapy selection, precise subtype identification and individualized prognosis are mandatory, but currently limited. Our aim was to refine subtyping and outcome prediction across main su...
Autores principales: | Büttner, Florian A., Winter, Stefan, Stühler, Viktoria, Rausch, Steffen, Hennenlotter, Jörg, Füssel, Susanne, Zastrow, Stefan, Meinhardt, Matthias, Toma, Marieta, Jerónimo, Carmen, Henrique, Rui, Miranda-Gonçalves, Vera, Kröger, Nils, Ribback, Silvia, Hartmann, Arndt, Agaimy, Abbas, Stöhr, Christine, Polifka, Iris, Fend, Falko, Scharpf, Marcus, Comperat, Eva, Wasinger, Gabriel, Moch, Holger, Stenzl, Arnulf, Gerlinger, Marco, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476269/ https://www.ncbi.nlm.nih.gov/pubmed/36109798 http://dx.doi.org/10.1186/s13073-022-01105-y |
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