Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches

Diminazene aceturate (DIZE), an antiparasitic, is an ACE2 activator, and studies show that activators of this enzyme may be beneficial for COVID-19, disease caused by SARS-CoV-2. Thus, the objective was to evaluate the in silico and in vitro affinity of diminazene aceturate against molecular targets...

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Detalles Bibliográficos
Autores principales: Santos, Esley S., Silva, Priscila C., Sousa, Paulo S.A., Aquino, Cristhyane C., Pacheco, Gabriella, Teixeira, Luiz F.L.S., Araujo, Alyne R., Sousa, Francisca B.M., Barros, Romulo O., Ramos, Ricardo M., Rocha, Jefferson A., Nicolau, Lucas A.D., Medeiros, Jand V.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476334/
https://www.ncbi.nlm.nih.gov/pubmed/36116513
http://dx.doi.org/10.1016/j.cbi.2022.110161

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