Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

The uneven worldwide vaccination coverage against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and emergence of variants escaping immunity call for broadly effective and easily deployable therapeutic agents. We have previously described the human single-chain scFv76 antibody, which r...

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Detalles Bibliográficos
Autores principales: Milazzo, Ferdinando M., Chaves-Sanjuan, Antonio, Minenkova, Olga, Santapaola, Daniela, Anastasi, Anna M., Battistuzzi, Gianfranco, Chiapparino, Caterina, Rosi, Antonio, Merlo Pich, Emilio, Albertoni, Claudio, Marra, Emanuele, Luberto, Laura, Viollet, Cécile, Spagnoli, Luigi G., Riccio, Anna, Rossi, Antonio, Santoro, M. Gabriella, Ballabio, Federico, Paissoni, Cristina, Camilloni, Carlo, Bolognesi, Martino, De Santis, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476359/
https://www.ncbi.nlm.nih.gov/pubmed/36114671
http://dx.doi.org/10.1016/j.ymthe.2022.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476359/
https://www.ncbi.nlm.nih.gov/pubmed/36114671
http://dx.doi.org/10.1016/j.ymthe.2022.09.010

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