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Mangiferin exerts neuroprotective activity against lead-induced toxicity and oxidative stress via Nrf2 pathway

OBJECTIVE: The study was designed to assess the beneficial role of mangiferin (MGN) in lead (Pb)-induced neurological damages in the activation of Nrf2-governed enzymes, genes and proteins. METHODS: A total of 96 weaned Wistar rats (48 males and 48 females, 26- to 27-day-old), weighing 50−80 g were...

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Detalles Bibliográficos
Autores principales: Li, Hao-wen, Lan, Tai-jin, Yun, Chen-xia, Yang, Ke-di, Du, Zheng-cai, Luo, Xue-fei, Hao, Er-wei, Deng, Jia-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476390/
https://www.ncbi.nlm.nih.gov/pubmed/36117559
http://dx.doi.org/10.1016/j.chmed.2019.12.002