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Mangiferin exerts neuroprotective activity against lead-induced toxicity and oxidative stress via Nrf2 pathway
OBJECTIVE: The study was designed to assess the beneficial role of mangiferin (MGN) in lead (Pb)-induced neurological damages in the activation of Nrf2-governed enzymes, genes and proteins. METHODS: A total of 96 weaned Wistar rats (48 males and 48 females, 26- to 27-day-old), weighing 50−80 g were...
Autores principales: | Li, Hao-wen, Lan, Tai-jin, Yun, Chen-xia, Yang, Ke-di, Du, Zheng-cai, Luo, Xue-fei, Hao, Er-wei, Deng, Jia-gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476390/ https://www.ncbi.nlm.nih.gov/pubmed/36117559 http://dx.doi.org/10.1016/j.chmed.2019.12.002 |
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