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Linking the phenotype of SNCA Triplication with PET-MRI imaging pattern and alpha-synuclein CSF seeding

Lewy-body pathology with aggregation of abnormal conformations of the protein alpha-synuclein (α-Syn) represent the histopathological hallmarks of Parkinson’s disease (PD). Genetic prototypes such as PD due to mutations in the alpha-synuclein gene (SNCA) offer the opportunity to evaluate α-Syn-relat...

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Detalles Bibliográficos
Autores principales:	Wurster, Isabel, Quadalti, Corinne, Rossi, Marcello, Hauser, Ann-Kathrin, Deuschle, Christian, Schulte, Claudia, Waniek, Katharina, Lachmann, Ingolf, la Fougere, Christian, Doppler, Kathrin, Gasser, Thomas, Bender, Benjamin, Parchi, Piero, Brockmann, Kathrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476413/ https://www.ncbi.nlm.nih.gov/pubmed/36109514 http://dx.doi.org/10.1038/s41531-022-00379-8

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