The P2Y(11) receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses

The cytoprotective ATP receptor P2Y(11) is upregulated during M2 macrophage differentiation and contributes to the anti-inflammatory properties of this macrophage subset. Here, we studied P2Y(11)-induced reprogramming of human M2 macrophages at the level of mRNA and protein expression. Upregulation...

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Detalles Bibliográficos
Autores principales: Klaver, Dominik, Gander, Hubert, Dobler, Gabriele, Rahm, Andrea, Thurnher, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476423/
https://www.ncbi.nlm.nih.gov/pubmed/36107259
http://dx.doi.org/10.1007/s00018-022-04548-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476423/
https://www.ncbi.nlm.nih.gov/pubmed/36107259
http://dx.doi.org/10.1007/s00018-022-04548-z

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