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The P2Y(11) receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses
The cytoprotective ATP receptor P2Y(11) is upregulated during M2 macrophage differentiation and contributes to the anti-inflammatory properties of this macrophage subset. Here, we studied P2Y(11)-induced reprogramming of human M2 macrophages at the level of mRNA and protein expression. Upregulation...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476423/ https://www.ncbi.nlm.nih.gov/pubmed/36107259 http://dx.doi.org/10.1007/s00018-022-04548-z |