Cargando…

Molecular mechanism of Chuanxiong Rhizoma in treating coronary artery diseases

OBJECTIVE: Most of the studies on the herb Chuanxiong Rhizoma (CR) have focused on the l-arginine-nitric oxide (NO) pathway, but the nitrate-nitrite-NO (NO(3)(−)–NO(2)(−)–NO) pathway was rarely investigated. Therefore, the aim of this study was to evaluate the effects and mechanisms of action of CR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Bang-qiao, Guo, Yu-hong, Liu, Yuan, Zhao, Yang-yang, Huang, Shan-mei, Wei, Xia-wei, Wang, Heng-sheng, Liu, Ruo-ya, Liu, Ying, Tang, Yao-ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476474/ https://www.ncbi.nlm.nih.gov/pubmed/36118926 http://dx.doi.org/10.1016/j.chmed.2021.03.001

Ejemplares similares

Phytochemical and Pharmacological Review of Da Chuanxiong Formula: A Famous Herb Pair Composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma for Headache
por: Wang, Lu, et al.
Publicado: (2013)

Lignan and Phthalide Derivatives from the Rhizome of Ligusticum chuanxiong (Rhizoma chuanxiong) and Evaluation of Their anti-Xanthine Oxidase Activities
por: Yang, Man-Li, et al.
Publicado: (2023)

Exploring the Potential Mechanism of Chuanxiong Rhizoma Treatment for Migraine Based on Systems Pharmacology
por: Wen, Xianhua, et al.
Publicado: (2021)

Effects of amendments on heavy metal immobilization and uptake by Rhizoma chuanxiong on copper and cadmium contaminated soil
por: Xie, Yanluo, et al.
Publicado: (2018)

Research on the potential mechanism of Chuanxiong Rhizoma on treating Diabetic Nephropathy based on network pharmacology
por: Hu, Shanshan, et al.
Publicado: (2020)

Reveal the Antimigraine Mechanism of Chuanxiong Rhizoma and Cyperi Rhizoma Based on the Integrated Analysis of Metabolomics and Network Pharmacology
por: Zhu, Zhiyao, et al.
Publicado: (2022)

The mechanisms of Chuanxiong Rhizoma in treating spinal cord injury based on network pharmacology and experimental verification
por: Tao, Bo, et al.
Publicado: (2021)

Pharmacokinetics effects of chuanxiong rhizoma on warfarin in pseudo germ-free rats
por: Li, Haigang, et al.
Publicado: (2023)

Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry
por: Wang, Fu-Rong, et al.
Publicado: (2017)

Characterization of thrombin/factor Xa inhibitors in Rhizoma Chuanxiong through UPLC-MS-based multivariate statistical analysis
por: Yang, Yi-Yao, et al.
Publicado: (2020)

Network Pharmacology and Molecular Docking Analyses of Mechanisms Underlying Effects of the Cyperi Rhizoma-Chuanxiong Rhizoma Herb Pair on Depression
por: Shi, Yanan, et al.
Publicado: (2021)

Detection and Risk Assessments of Multi-Pesticides in Traditional Chinese Medicine Chuanxiong Rhizoma by LC/MS-MS and GC/MS-MS
por: Zhang, Delin, et al.
Publicado: (2022)

Cardiovascular Actions and Therapeutic Potential of Tetramethylpyrazine (Active Component Isolated from Rhizoma Chuanxiong): Roles and Mechanisms
por: Guo, Ming, et al.
Publicado: (2016)

Uncovering the Neuroprotective Effect of Hedysarum multijugum Maxim-Chuanxiong Rhizoma Compound on Cerebral Infarction through Quantitative Proteomics
por: Wang, Guozuo, et al.
Publicado: (2022)

Novel phthalide derivatives identified from Ligusticum chuanxiong (Chuanxiong)
por: Yang, Jun, et al.
Publicado: (2016)

The Effect of Hedysarum multijugum Maxim.-Chuanxiong rhizoma Compound on Ischemic Stroke: A Research Based on Network and Experimental Pharmacology
por: Yang, Kailin, et al.
Publicado: (2020)

Fingerprint analysis of processed Rhizoma Chuanxiong by high-performance liquid chromatography coupled with diode array detection
por: Fang, Jia-Yan, et al.
Publicado: (2015)

Interaction of lobed kudzuvine root, rhizoma chuanxiong with both acetylcholinesterase and beta-amyloid (Aβ1-42)
por: Shuai, Li, et al.
Publicado: (2013)

Key Phytochemicals and Biological Functions of Chuanxiong Rhizoma Against Ischemic Stroke: A Network Pharmacology and Experimental Assessment
por: Zeng, Peng, et al.
Publicado: (2021)

A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Chuanxiong Rhizoma in Alzheimer’s Disease
por: Zeng, Peng, et al.
Publicado: (2022)

Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification
por: He, Shasha, et al.
Publicado: (2023)

Nephroprotective mechanisms of Rhizoma Chuanxiong and Radix et Rhizoma Rhei against acute renal injury and renal fibrosis based on network pharmacology and experimental validation
por: Li, Jun, et al.
Publicado: (2023)

Comparative Study on Pharmacokinetics of Four Active Compounds in Rat Plasma after Oral Administration of Raw and Wine Processed Chuanxiong Rhizoma
por: Ning, Yan, et al.
Publicado: (2019)

Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of “Chuanxiong Rhizoma: Radix Salviae miltiorrhizae” Herb Couples in the Treatment of Preeclampsia
por: Wei, Jing, et al.
Publicado: (2022)

Anti-Migraine Effect of the Herbal Combination of Chuanxiong Rhizoma and Cyperi Rhizoma and UPLC-MS/MS Method for the Simultaneous Quantification of the Active Constituents in Rat Serum and Cerebral Cortex
por: Wu, Sha, et al.
Publicado: (2019)

Effect of Ultrasonic Penetration with Volatile Oil of Olibanum and Chuanxiong Rhizoma on Acute Knee Synovitis Induced by Sports Training: An Open-Label Randomized Controlled Study
por: Xuan, Qiwen, et al.
Publicado: (2022)

A Reasonable Evaluation of Chuanxiong Rhizoma Processing with Wine through Comparative Pharmacokinetic Study of Bioactive Components: Dominant Effect on Middle Cerebral Artery Occlusion Model Rats
por: Pei, Ke, et al.
Publicado: (2022)

Identification and Comparative Quantification of Bio-Active Phthalides in Essential Oils from Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong
por: Tang, Yuping, et al.
Publicado: (2010)

Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry
por: Zhan, Janis Ya-xian, et al.
Publicado: (2013)

Simultaneous Determination of Night Effective Constituents and Correlation Analysis of Multiconstituents and Antiplatelet Aggregation Bioactivity In Vitro in Chuanxiong Rhizoma Subjected to Different Decoction Times
por: Zhang, Peihua, et al.
Publicado: (2019)

The variation in the major constituents of the dried rhizome of Ligusticum chuanxiong (Chuanxiong) after herbal processing
por: Yi, Tao, et al.
Publicado: (2016)

Transcriptional profiling of uterine leiomyoma rats treated by a traditional herb pair, Curcumae rhizoma and Sparganii rhizoma
por: Yu, Cheng Hao, et al.
Publicado: (2019)

Network Pharmacology-Based Investigation on Therapeutic Mechanisms of the Angelica dahurica Radix and Ligusticum chuanxiong Rhizoma Herb Pair for Anti-Migraine Effect
por: Thanh, Chu Duc, et al.
Publicado: (2022)

Retracted: Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of “Chuanxiong Rhizoma: Radix Salviae miltiorrhizae” Herb Couples in the Treatment of Preeclampsia
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy
por: Li, ChangYan, et al.
Publicado: (2022)

Exploring the Regulatory Mechanism of Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound on HIF-VEGF Pathway and Cerebral Ischemia-Reperfusion Injury’s Biological Network Based on Systematic Pharmacology
por: Yang, Kailin, et al.
Publicado: (2021)

Antifungal Effects and Active Components of Ligusticum chuanxiong
por: Chen, Huabao, et al.
Publicado: (2022)

Research Advances in Cardio-Cerebrovascular Diseases of Ligusticum chuanxiong Hort.
por: Li, Dan, et al.
Publicado: (2022)

Muscle Fatigue-Alleviating Effects of a Prescription Composed of Polygonati Rhizoma and Notoginseng Radix et Rhizoma
por: Yang, Ya-Qin, et al.
Publicado: (2020)

A Compositive Strategy to Study the Pharmacokinetics of TCMs: Taking Coptidis Rhizoma, and Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma as Examples
por: Li, Qiao, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pm0tvv3uag001nouq9eagj9u5d