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Recent Advances in the Prins Reaction

[Image: see text] The Prins reaction is a very convenient synthetic platform for the preparation of oxygen-containing heterocyclic compounds, especially tetrahydropyrans and tetrahydrofurans. While this reaction has been extensively used by synthetic chemists since its discovery, the last years have...

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Detalles Bibliográficos
Autores principales: Reyes, Efraim, Prieto, Liher, Uria, Uxue, Carrillo, Luisa, Vicario, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476534/
https://www.ncbi.nlm.nih.gov/pubmed/36120064
http://dx.doi.org/10.1021/acsomega.2c04765
Descripción
Sumario:[Image: see text] The Prins reaction is a very convenient synthetic platform for the preparation of oxygen-containing heterocyclic compounds, especially tetrahydropyrans and tetrahydrofurans. While this reaction has been extensively used by synthetic chemists since its discovery, the last years have witnessed impressive improvements in its performance and scope and especially in the development of new catalytic and enantioselective versions. This mini-review presents these recent advances through selected representative examples.