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Comparative pharmacokinetics of baicalin and geniposide in juvenile and adult rats after oral administration of Qingkailing Granules

OBJECTIVE: To explore the effect of age on Qingkailing Granules disposition by comparing the pharmacokinetics of geniposide and baicalin in juvenile and adult rats. METHODS: A simple and rapid LC-MS/MS method was developed and validated to simultaneously determine geniposide and baicalin in rat plas...

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Detalles Bibliográficos
Autores principales: Li, Ting-yu, Li, Zhong, Yang, Xiao-yan, Zhao, Xin-yu, Zhang, Xu, Zhao, Xin-bo, Wang, Song, Huo, Xiao-kui, Shi, Xiao-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476668/
https://www.ncbi.nlm.nih.gov/pubmed/36120172
http://dx.doi.org/10.1016/j.chmed.2020.05.011