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Comparative pharmacokinetics of baicalin and geniposide in juvenile and adult rats after oral administration of Qingkailing Granules
OBJECTIVE: To explore the effect of age on Qingkailing Granules disposition by comparing the pharmacokinetics of geniposide and baicalin in juvenile and adult rats. METHODS: A simple and rapid LC-MS/MS method was developed and validated to simultaneously determine geniposide and baicalin in rat plas...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476668/ https://www.ncbi.nlm.nih.gov/pubmed/36120172 http://dx.doi.org/10.1016/j.chmed.2020.05.011 |