RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma

BACKGROUND: Severe hypoxia is a prominent character of pancreatic ductal adenocarcinoma (PDAC) microenvironment. In the process of gemcitabine based chemotherapy, PDAC cells are insulted from replication stresses co-induced by hypoxia and gemcitabine. However, PDAC cells get outstanding abilities to...

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Detalles Bibliográficos
Autores principales: Tu, Qiu, Liu, Xiuyun, Yao, Xiaoqing, Li, Ruixue, Liu, Gaojing, Jiang, Honglv, Li, Kaiqin, Chen, Qiongfang, Huang, Xiaoyan, Chang, Qing, Xu, Guoqiang, Zhu, Hong, Shi, Peng, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476698/
https://www.ncbi.nlm.nih.gov/pubmed/36109793
http://dx.doi.org/10.1186/s13046-022-02490-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476698/
https://www.ncbi.nlm.nih.gov/pubmed/36109793
http://dx.doi.org/10.1186/s13046-022-02490-3

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