Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer

Chronic atrophic gastritis (CAG), a common disease of digestive system, is an extremely important cause of gastric cancer (GC). The occurrence and development of CAG involves the abnormality of multiple signaling pathways. Traditional Chinese medicines (TCMs) has the advantages of mild action, multi...

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Autores principales: Liu, Xinnan, Wang, Shuping, Li, Jingyang, Zhang, Jingze, Liu, Dailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476726/
https://www.ncbi.nlm.nih.gov/pubmed/36120132
http://dx.doi.org/10.1016/j.chmed.2021.10.008
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author Liu, Xinnan
Wang, Shuping
Li, Jingyang
Zhang, Jingze
Liu, Dailin
author_facet Liu, Xinnan
Wang, Shuping
Li, Jingyang
Zhang, Jingze
Liu, Dailin
author_sort Liu, Xinnan
collection PubMed
description Chronic atrophic gastritis (CAG), a common disease of digestive system, is an extremely important cause of gastric cancer (GC). The occurrence and development of CAG involves the abnormality of multiple signaling pathways. Traditional Chinese medicines (TCMs) has the advantages of mild action, multi-target and small adverse reaction, etc., which broadens the way for the treatment of the disease, and TCMs can play a therapeutic role by regulating multiple signaling pathways. In this review, based on the related experiments of TCMs and Chinese herbal compounds in recent years, the related literatures were searched and 10 kinds of signaling pathways involved were summarized, in order to provide a reference for further research on reversing or delaying the progress of CAG and preventing gastric cancer.
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spelling pubmed-94767262022-09-16 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer Liu, Xinnan Wang, Shuping Li, Jingyang Zhang, Jingze Liu, Dailin Chin Herb Med Review Chronic atrophic gastritis (CAG), a common disease of digestive system, is an extremely important cause of gastric cancer (GC). The occurrence and development of CAG involves the abnormality of multiple signaling pathways. Traditional Chinese medicines (TCMs) has the advantages of mild action, multi-target and small adverse reaction, etc., which broadens the way for the treatment of the disease, and TCMs can play a therapeutic role by regulating multiple signaling pathways. In this review, based on the related experiments of TCMs and Chinese herbal compounds in recent years, the related literatures were searched and 10 kinds of signaling pathways involved were summarized, in order to provide a reference for further research on reversing or delaying the progress of CAG and preventing gastric cancer. Elsevier 2021-12-21 /pmc/articles/PMC9476726/ /pubmed/36120132 http://dx.doi.org/10.1016/j.chmed.2021.10.008 Text en © 2021 Published by Elsevier B.V. on behalf of Editorial Board of Chinese Herbal Medicines. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Liu, Xinnan
Wang, Shuping
Li, Jingyang
Zhang, Jingze
Liu, Dailin
Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
title Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
title_full Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
title_fullStr Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
title_full_unstemmed Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
title_short Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
title_sort regulatory effect of traditional chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476726/
https://www.ncbi.nlm.nih.gov/pubmed/36120132
http://dx.doi.org/10.1016/j.chmed.2021.10.008
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