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Effects of total iridoid glycosides of Picrorhiza scrophulariiflora against non-alcoholic steatohepatitis rats induced by high-fat and high-sugar diet through regulation of lipid metabolism
OBJECTIVE: To investigate the therapeutic effect of total iridoid glycosides of Picrorhiza scrophulariiflora (TIGP) on non-alcoholic steatohepatitis (NASH). METHODS: SD rats were fed with high-fat and high-sugar diet for 8 weeks to establish NASH. TIGP were given orally at doses of 20, 40 and 80 mg/...
Autores principales: | Xu, Xu, Wang, Wei-ting, Zhao, Zhuan-you, Xi, Wen-gong, Yu, Bing, Hao, Chun-hua, Li, Xin, Hou, Wen-bin, Tang, Li-da |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476743/ https://www.ncbi.nlm.nih.gov/pubmed/36117562 http://dx.doi.org/10.1016/j.chmed.2019.12.005 |
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