Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition

OBJECTIVE: Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in substantia nigra (SN). Our previous study demonstrated kukoamine A (KuA) to exhibit strong neuroprotective effects through antioxidative stress, and autophagy in MPTP/MPP(+)-induced PD models in vivo and...

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Detalles Bibliográficos
Autores principales: Li, Xin, Jiang, Xiao-wen, Chu, Hai-xiao, Zhao, Qing-chun, Ding, Huai-wei, Cai, Chao-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476749/
https://www.ncbi.nlm.nih.gov/pubmed/36117765
http://dx.doi.org/10.1016/j.chmed.2020.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476749/
https://www.ncbi.nlm.nih.gov/pubmed/36117765
http://dx.doi.org/10.1016/j.chmed.2020.12.004

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