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Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition
OBJECTIVE: Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in substantia nigra (SN). Our previous study demonstrated kukoamine A (KuA) to exhibit strong neuroprotective effects through antioxidative stress, and autophagy in MPTP/MPP(+)-induced PD models in vivo and...
Autores principales: | Li, Xin, Jiang, Xiao-wen, Chu, Hai-xiao, Zhao, Qing-chun, Ding, Huai-wei, Cai, Chao-hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476749/ https://www.ncbi.nlm.nih.gov/pubmed/36117765 http://dx.doi.org/10.1016/j.chmed.2020.12.004 |
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