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Novel therapeutic diiminoquinone exhibits anticancer effects on human colorectal cancer cells in two-dimensional and three-dimensional in vitro models

BACKGROUND: Colorectal cancer (CRC) is the second leading cause of cancer-related mortality. Cancer stem cells (CSCs) in CRC, which are spared by many chemotherapeutics, have tumorigenic capacity and are believed to be the reason behind cancer relapse. So far, there have been no effective drugs to t...

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Detalles Bibliográficos
Autores principales: Monzer, Alissar, Wakimian, Kevork, Ballout, Farah, Al Bitar, Samar, Yehya, Amani, Kanso, Mariam, Saheb, Nour, Tawil, Ayman, Doughan, Samer, Hussein, Maher, Mukherji, Deborah, Faraj, Walid, Gali-Muhtasib, Hala, Abou-Kheir, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476858/
https://www.ncbi.nlm.nih.gov/pubmed/36156922
http://dx.doi.org/10.3748/wjg.v28.i33.4787