Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones

A transfer hydrosilylation of ketones employing silyl formates as hydrosilane surrogates under mild conditions is presented. A total of 24 examples of ketones have been successfully converted to their corresponding silyl ethers with 61–99% yields in the presence of a PN(H)P-based ruthenium catalyst...

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Autores principales: Romero, R. Martin, Thyagarajan, Neethu, Hellou, Nora, Chauvier, Clément, Godou, Timothé, Anthore-Dalion, Lucile, Cantat, Thibault
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476892/
https://www.ncbi.nlm.nih.gov/pubmed/35522145
http://dx.doi.org/10.1039/d2cc00666a
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author Romero, R. Martin
Thyagarajan, Neethu
Hellou, Nora
Chauvier, Clément
Godou, Timothé
Anthore-Dalion, Lucile
Cantat, Thibault
author_facet Romero, R. Martin
Thyagarajan, Neethu
Hellou, Nora
Chauvier, Clément
Godou, Timothé
Anthore-Dalion, Lucile
Cantat, Thibault
author_sort Romero, R. Martin
collection PubMed
description A transfer hydrosilylation of ketones employing silyl formates as hydrosilane surrogates under mild conditions is presented. A total of 24 examples of ketones have been successfully converted to their corresponding silyl ethers with 61–99% yields in the presence of a PN(H)P-based ruthenium catalyst and silyl formate reagent. The crucial role of the ligand for the transformation is demonstrated.
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spelling pubmed-94768922022-10-20 Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones Romero, R. Martin Thyagarajan, Neethu Hellou, Nora Chauvier, Clément Godou, Timothé Anthore-Dalion, Lucile Cantat, Thibault Chem Commun (Camb) Chemistry A transfer hydrosilylation of ketones employing silyl formates as hydrosilane surrogates under mild conditions is presented. A total of 24 examples of ketones have been successfully converted to their corresponding silyl ethers with 61–99% yields in the presence of a PN(H)P-based ruthenium catalyst and silyl formate reagent. The crucial role of the ligand for the transformation is demonstrated. The Royal Society of Chemistry 2022-05-03 /pmc/articles/PMC9476892/ /pubmed/35522145 http://dx.doi.org/10.1039/d2cc00666a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Romero, R. Martin
Thyagarajan, Neethu
Hellou, Nora
Chauvier, Clément
Godou, Timothé
Anthore-Dalion, Lucile
Cantat, Thibault
Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
title Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
title_full Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
title_fullStr Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
title_full_unstemmed Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
title_short Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
title_sort silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476892/
https://www.ncbi.nlm.nih.gov/pubmed/35522145
http://dx.doi.org/10.1039/d2cc00666a
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