Cargando…

The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway

The regulation of the mRNA decay activator Tristetraprolin (TTP) by the p38 mitogen-activated protein kinase (MAPK) pathway during the mammalian inflammatory response represents a paradigm for the control of mRNA turnover by signaling. TTP activity is regulated through multiple phosphorylation sites...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carreño, Alberto, Lykke-Andersen, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476947/ https://www.ncbi.nlm.nih.gov/pubmed/35920669 http://dx.doi.org/10.1128/mcb.00055-22

Ejemplares similares

hnRNP F Complexes with Tristetraprolin and Stimulates ARE-mRNA Decay
por: Reznik, Boris, et al.
Publicado: (2014)

The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU–Rich Element–Dependent Translation
por: Tiedje, Christopher, et al.
Publicado: (2012)

Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements
por: Fu, Rui, et al.
Publicado: (2016)

MAPK p38 regulates inflammatory gene expression via tristetraprolin: Doing good by stealth
por: O’Neil, J.D., et al.
Publicado: (2018)

Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation
por: Kratochvill, Franz, et al.
Publicado: (2011)

Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2
por: Suzuki, Toru, et al.
Publicado: (2022)

P38 activation induces the dissociation of tristetraprolin from Argonaute 2 to increase ARE-mRNA stabilization
por: Qi, Mei-Yan, et al.
Publicado: (2018)

Role of Cnot6l in maternal mRNA turnover
por: Horvat, Filip, et al.
Publicado: (2018)

The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
por: Mauxion, Fabienne, et al.
Publicado: (2022)

Intrinsically disordered regions of tristetraprolin and DCP2 directly interact to mediate decay of ARE-mRNA
por: Maciej, Vincent D, et al.
Publicado: (2022)

CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State
por: Zheng, Xiaofeng, et al.
Publicado: (2016)

CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner
por: Mohamed, Haytham Mohamed Aly, et al.
Publicado: (2022)

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38(MAPK)-induced heat shock protein 27 phosphorylation
por: Shiryaev, Alexey, et al.
Publicado: (2011)

CNOT3 interacts with the Aurora B and MAPK/ERK kinases to promote survival of differentiating mesendodermal progenitor cells
por: Sarkar, Moumita, et al.
Publicado: (2021)

Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in Inflammatory Arthritis: A Narrative of the Emergence of MAPK-Activated Protein Kinase Inhibitors (MK2i)
por: Ganguly, Payal, et al.
Publicado: (2023)

IL‐33 regulates cytokine production and neutrophil recruitment via the p38 MAPK‐activated kinases MK2/3
por: McCarthy, Pierre C, et al.
Publicado: (2018)

Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway
por: O'Dea, Kieran P., et al.
Publicado: (2011)

Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway
por: Maruyama, Junichi, et al.
Publicado: (2016)

The p38(MAPK)-MK2 Signaling Axis as a Critical Link Between Inflammation and Synaptic Transmission
por: Beamer, Edward, et al.
Publicado: (2021)

p38(MAPK)/MK2 signaling stimulates host cells autophagy pathways to restrict Salmonella infection
por: Suwandi, Abdulhadi, et al.
Publicado: (2023)

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation
por: Liu, Xin, et al.
Publicado: (2016)

Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay
por: Durand, Sébastien, et al.
Publicado: (2016)

Roles of Tristetraprolin in Tumorigenesis
por: Park, Jeong-Min, et al.
Publicado: (2018)

p38(MAPK)/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex
por: Tiedje, Christopher, et al.
Publicado: (2015)

Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis
por: Krishnamurthy, Pranathi Meda, et al.
Publicado: (2017)

A Competition between Stimulators and Antagonists of Upf Complex Recruitment Governs Human Nonsense-Mediated mRNA Decay
por: Singh, Guramrit, et al.
Publicado: (2008)

Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin
por: Rahman, Md. Mostafizur, et al.
Publicado: (2015)

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury
por: Ashraf, Muhammad Imtiaz, et al.
Publicado: (2014)

Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis
por: Ronkina, Natalia, et al.
Publicado: (2016)

Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals
por: Wang, Chun, et al.
Publicado: (2018)

Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling
por: Zhang, Hai-feng, et al.
Publicado: (2020)

Luteolin Inhibits Inflammatory Responses via p38/MK2/TTP-mediated mRNA Stability
por: Wu, Wanling, et al.
Publicado: (2013)

Role of Tristetraprolin in the Resolution of Inflammation
por: Rappl, Peter, et al.
Publicado: (2021)

CNOT6 regulates a novel pattern of mRNA deadenylation during oocyte meiotic maturation
por: Vieux, Karl-Frédéric, et al.
Publicado: (2018)

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin
por: Ross, Ewan A., et al.
Publicado: (2015)

Tristetraprolin Gene Single-Nucleotide Polymorphisms and mRNA Level in Patients With Rheumatoid Arthritis
por: Yang, Xiaoke, et al.
Publicado: (2021)

Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells
por: Lynch, Katherine D., et al.
Publicado: (2023)

Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation
por: Zhou, Bingying, et al.
Publicado: (2017)

The transcriptional regulation and cell-specific expression of the MAPK-activated protein kinase MK5
por: Gerits, Nancy, et al.
Publicado: (2009)

Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice
por: Saaoud, Fatma, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hnliveik0d91eofo1ht096v4a6